February 28th News: It is reported that Genomatica, a U.S.-based company, has achieved large-scale production of bio-based BDO at a ten-thousand-ton level and has obtained EU low-carbon certification. This poses long-term substitution pressure on the traditional coal-based BDO production route. Chempricehub's analysis of 1,4-butanediol, with a bullish-bearish rating: -1. Genomatica's achievement of large-scale production of bio-based 1,4-butanediol at a ten-thousand-ton level and its EU low-carbon certification will significantly increase market supply and encourage downstream industries to shift toward more environmentally friendly bio-based routes. This will lead to a reduction in demand for traditional coal-based 1,4-butanediol, thereby exerting sustained downward pressure on spot prices. The rating is generally bearish, as the impact, though long-term, indicates a clear substitution trend.