How does ketoprofen's anti-inflammatory potency compare with ibuprofen in clinical use?

How does ketoprofen's anti-inflammatory potency compare with ibuprofen in clinical use?
Ketoprofen and ibuprofen are both arylpropionic acid NSAIDs that work by inhibiting prostaglandin synthesis. However, ketoprofen has notably stronger anti-inflammatory effects than ibuprofen, with lower side effects and toxicity at comparable doses. In dental practice, clinicians often prescribe ketoprofen 80 mg or ibuprofen 600 mg for true anti-inflammatory pain relief after procedures, while antibiotics like metronidazole are used separately to prevent bacterial infection, not to treat inflammation. Ketoprofen is indicated for rheumatoid arthritis, osteoarthritis, ankylosing spondylitis, gouty arthritis, dysmenorrhea, dental pain, postoperative pain, and cancer pain. Its short half-life has led to sustained-release formulations to extend therapeutic duration. The S-enantiomer (dexketoprofen) shows 30 to 75,000 times higher COX-2 inhibition than the R-form, and 12.5-25 mg dexketoprofen trometamol matches 25-50 mg racemic ketoprofen in bioactivity.