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What are the key physical properties and solubility data buyers should know for sec-butanol?

Wei Zhang
Published on 2026-08-08

What are the key physical properties and solubility data buyers should know for sec-butanol?
Sec-butanol is a flammable, colorless liquid with a wine-like odor, miscible with most organic solvents and soluble in about three parts water. Historical solubility figures were often misquoted as 12.5 g per 100 g water at 20°C, an error traced to a 1901 paper and propagated by Beilstein's handbook. Correct values are approximately 26.0% at 20°C, 22.5% at 25°C, and 18.0% at 30°C. This temperature-dependent solubility matters for solvent blending, extraction processes, and waste-water handling. The compound also forms azeotropes with water, which influences distillation design. Buyers should verify technical datasheets against these corrected values when specifying grades for pharmaceutical or fine chemical applications.

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  • Marcus Hayes 2026-08-09 15:00
    Also note sec-butanol is chiral, typically sold as a racemic mixture. For specialized uses like asymmetric synthesis or certain pharmaceutical intermediates, enantiopure grades command premiums. Always confirm stereochemical composition in your purchase specification to avoid costly purification surprises.
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