Barbituric acid Price Chart & Market Analysis 2026

Barbituric acid Price Information

Newest Price 141,630

Price Date 20210321

Day's Change 0

Day's Range 141,630 - 141,630

Month's Change 0

Month's Range 0 - 0

Year's Change 0

Year's Range 0 - 0

Opinions

How does barbituric acid's molecular structure impact its market positioning in pharmaceuticals?

From a procurement angle, purity specs matter more than structural nuance. Barbituric acid for pharmaceutical intermediate use typically requires higher purity than industrial grades. Also, regulatory oversight on barbiturate derivatives can tighten supply chains, so verifying downstream compliance is prudent before committing to long-term contracts.

What feedstock trends should barbituric acid buyers monitor in 2025?

Don't overlook logistics—barbituric acid is often shipped as a fine chemical powder, and packaging costs plus freight rates have been volatile. Also, some producers integrate backward into malonic acid, giving them cost advantages. When comparing quotes, ask about feedstock sourcing to gauge pricing stability over the quarter.

Why is barbituric acid demand shrinking despite its role as a key pharmaceutical intermediate?

The shift away from barbiturate sedatives is irreversible, but barbituric acid still finds use in producing compounds like riboflavin and certain cephalosporins. Buyers should watch feedstock costs—malonic acid and urea—which directly influence production economics. Supply is concentrated among a few Chinese producers, so any capacity changes there can quickly move prices.

Overview

Barbituric acid (malonylurea, 2,4,6-pyrimidinetrione, CAS 67-52-7) is a white crystalline powder with a strong acidic aqueous solution, serving as the parent compound for barbiturate drugs and a key intermediate in organic synthesis.

Pharmaceutical: the core scaffold for barbiturates; substitution at the C5 position yields sedative-hypnotic, anticonvulsant, and anesthetic agents such as phenobarbital.
Chemical synthesis: a building block for preparing 5-aryl and 5,5-disubstituted derivatives via palladium-catalyzed coupling and related routes.
Research: widely used in medicinal chemistry studies of lead compounds and CNS-active drug design.

China's production landscape centers on pharmaceutical intermediates and fine chemical grades, with output primarily serving domestic API synthesis and export to generic drug markets. Manufacturing relies on urea-malonate condensation routes, and capacity is broadly sufficient to meet domestic demand.

Key domestic producers:
Hebei Chengxin – pharmaceutical intermediate grade.
Nantong Tendenci Chemical – fine chemical and research grade.

Properties

Name

Barbituric acid

2,4,6(1H,3H,5H)-Pyrimidinetrione

2,4,6-Trihydroxypyrimidine

6-hydroxypyrimidine-2,4(1H,3H)-dione

Babituric acid dihydrate

CAS Number

67-52-7

EINECS No.

200-658-0

Risk Codes

24/25

Safety Description

36/37/38

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Barbituric acid Price Information

Opinions

How does barbituric acid's molecular structure impact its market positioning in pharmaceuticals?

What feedstock trends should barbituric acid buyers monitor in 2025?

Why is barbituric acid demand shrinking despite its role as a key pharmaceutical intermediate?

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